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Bridge to Transplant

PD is the ideal bridge to kidney transplant associated with favorable post-transplant outcomes¹

Pre-transplant PD is associated with lower 5-year mortality after transplant than HD¹
Pre-transplant PD was associated with lower risk of delayed graft function* Compared with HD¹ (*unadjusted)

The 16 studies included in this meta-analysis showed favorable post-transplant outcomes with PD

Chart showing significant findings from a meta-analysis — Significant heterogeneity was observed for all outcomes:
12 = 72.7%, 12 = 59.9%, and 12 = 66.8%, respectively. Adapted from Joachim E, et al. Perit Dial Int. 2017;37(3):259-265.

Six of the 16 studies demonstrated improvement of 5-year mortality in PD patients as compared to HD patients¹

Charts showing five-year post-transplant mortality and graft survival — Adapted from Joachim E, et al. Perit Dial Int. 2017;37(3):259-265.

This meta-analysis suggests that PD may be the preferred dialysis modality for patients who expect to receive a renal transplant¹

Meta-analysis methodology¹

Two independent authors searched English-language literature from January 1, 1980, through August 31, 2014, national conference proceedings, and reference lists
The authors used combinations of terms related to dialysis (hemodialysis, peritoneal dialysis, or renal replacement therapy), kidney transplant, and outcomes
Studies were included if they measured any of the 3 post-transplant study outcomes in both pre-transplant HD and PD

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References